LMP1208H: Molecular clinical microbiology and infectious diseases

Who can attend

You must be registered in our graduate program (PhD or MSc) to attend this course.

You are expected to have a background in infectious diseases, microbiology and molecular biology.

Course description

You will learn about:

  • genomic/proteomic applications for the diagnosis, control, and management of infectious diseases.
  • practical and theoretical aspects of the specialist area of medical microbiology and the necessary skills to undertake individual and collaborative research in this field.
  • new methods including next-generation sequencing, high resolution proteomics, and bioinformatics.

Course coordinators

Dr. Nahuel Fittipaldi
nahuel.fittipaldi@oahpp.ca

Dr. Roberto Melano
roberto.melano@oahpp.ca

Dr. Vanessa Tran
vanessa.tran@oahpp.ca

lmp.grad@utoronto.ca for administrative queries.

Timings and location

This course is offered every year in the Winter term.

Wednesdays 9:30 am - 12:30 pm (two lectures per session)

Location: Synchronous online delivery (Zoom)

Evaluation methods

Student presentation of a current research paper - 30%

Written critiques of scientific papers discussed in lectures - 20%

Participation - 10%

Take-home research proposal (report will be due 60 days after assignment) - 40%

Late submissions will incur a penalty of a 5% reduction in marks for each day late.

Schedule

A lecture takes place at 9:30 am and at 11:00 am in each session.

date topic
January 13, 2021

9:30 am: Introduction

January 20, 2021

9:30 am: Genomics and bioinformatics in public health microbiology

  • Dr. John Nash, Chief, Innovation and Application Development; Senior Research Scientist - Public Health Agency of Canada

11 am: Genomics applied to the study of bacterial epidemics

January 27, 2021

9:30 am: New generation sequencing strategies applied to pathogen discovery

11 am: The pulmonary microbiota and human health

February 3, 2021

9:30 am: Molecular testing in routine clinical microbiology laboratories: an epidemiologist’s perspective

11 am: Molecular methods in a hospital microbiology laboratory

February 10, 2021

9:30 am: Responding to emerging infectious diseases on a public health level

11 am: COVID-19 & Influenza - molecular approaches

February 17, 2021

9:30 am: Understanding HIV transmission

  • Dr. Rupert Kaul, Professor and Division Director, Division of Infectious Diseases, University of Toronto, Division head, Infectious Diseases, at the University Health Network

11 am: Molecular Approaches to Medical Parasitology

  • Dr. Antoine Corbeil, MD
February 24, 2021

9:30 am: Molecular evolution of antimicrobial resistance in Neisseria gonorrhoeae

11 am: Molecular and proteomic applications in clinical mycology

March 3, 2021

9:30 am: Molecular detection and dissemination of antibiotic resistance

11 am: Discovery of new antimicrobial agents

  • Dr. Gerry Wright, Professor in the Department of Biochemistry and Biomedical Sciences, and Canada Research Chair in Antibiotic Biochemistry at McMaster University
March 10, 2021

9:30 am: COVID-19 serology

11 am: Hepatitis

March 17, 2021

9:30 am: Understanding vaccine effectiveness using laboratory data

  • Dr. Sarah Buchan, Scientist at Public Health Ontario and Assistant Professor, Dalla Lana School of Public Health, University of Toronto

11 am: Vaccine efficiency - Measles

  • Dr. Shelly Bollotin, Scientist at Public Health Ontario and Assistant Professor, Dalla Lana School of Public Health, University of Toronto
March 24, 2021

9:30 am: Molecular microbiology and vaccine development

  • Dr. Scott Gray-Owen, Professor in the Department of Molecular Genetics, University of Toronto

11 am: Vaccine development and formulation: an industrial perspective

  • Dr. Fernando Ausar, Global Bioprocess Expert- Formulation and Adjuvant at Sanofi Pasteur Vaccines Canada