LMP1107H: Bioinformatics in LMP

Who can attend

There are no prerequisites for this course.

Course description

Bioinformatics is used in all areas of biology.

You will learn about approaches used in the analysis of molecular sequence data.

This course is not intended for those who primarily intend to use bioinformatics, but rather to allow you to understand results of work that complements third research approaches.

Each week, we will discuss a different topic with hands-on use of online tools to analyze molecular data.

Course coordinator

Dr. David Irwin

david.irwin@utoronto.ca

lmp.grad@utoronto.ca for administrative queries.

Timings and location

This course is offered every year in the Winter session.

Thursdays 10 am – 12 pm

Location: Synchronous online delivery via Blackboard Collaborate (through Quercus).

Evaluation methods

Weekly assignments - 50% (5 x 10%). These will use resources discussed in the lectures.

Term project - 25%. Your project will be assigned in week three and you will submit it in week six. You will use an assigned sequence for each of the aspects discussed in this course.

Final exam - 25%. You will be examined on theoretical aspects of the methods and the interpretation of results of bioinformatic analyses.

Schedule

All sessions are led by Dr. David Irwin.

date topic
March 4, 2021 Databases / Data retrieval / Blast searches
March 11, 2021 Analysis of DNA sequences (e.g., Mapping restriction sites, Primer site prediction, ORF prediction, Promoter/enhancer prediction)
March 18, 2021 Analysis of Protein sequences (e.g., Protein processing sites, Phosphorylation sites, Cellular localization)
March 25, 2021 Alignment of Sequences (DNA and protein)
April 1, 2021 Evolutionary analysis
April 8, 2021 Final Exam