LMP365H1 - Neoplasia 20L 4P

Course description

A general introduction to the cellular and molecular aspects of cancer and its etiology.

The laboratory component presents the range of benign and malignant tumor types at the gross and histological levels.

Pathophysiology of cancer – tumorigenesis, invasion/ metastases, analytical and therapeutic strategies.

Course coordinator

Dr. Harry Elsholtz

Office address: 1 King’s College Circle, MSB 6207

h.elsholtz@utoronto.ca

Teaching assistant

Sachin Kumar

sachin.kumar@mail.utoronto.ca

Term  Winter 2021
Class location and time

Thursday 1:00-3:00 pm

Online Synchronous

Tutorial location and time To be announced
Office hours Meeting times can be arranged with course coordinator

Course details

  • Hours: 20L/4P
  • Corequisite: LMP340H1 or permission of department
  • Exclusions: none
  • Distribution requirements: Science
  • Breadth requirement: Living Things and Their Environment (4)
  • Enrolment limits: 35 students

Student evaluation

Online Pathology Lab Test: 20%

Online Midterm Test: 35%

Online Final Exam: 45%

See information on Academic Integrity

 

Schedule

Date Topic Instructor
January 13

Introduction and overview

Epidemiology

DNA Damage/ Repair

Harry Elsholtz
January 21 BRCA in Cancer Razqallah Hakem
January 28 MMR and Hypermutation in Human Cancer Adam Shlien
February 4 Pathology Laboratory I

Sachin Kumar / Irene Xie

Susan Armstrong

February 11

Pathology Laboratory II

Lab Test (20%)

Sachin Kumar / Irene Xie

Susan Armstrong

February 18 Reading Week  
February 25 Online Midterm Test (35%)

Harry Elsholtz

Sachin Kumar

March 4

Cancer Hallmarks

Hypoxia and Cancer Biology

Michael Ohh
March 11 Cancer Invasion and Metastasis Marco Magalhaes
March 18 Computational Biology in Cancer Bo Wang
March 25 Cancer Metabolism and Metastasis Eldad Zacksenhaus
April 1 Cancer Biomarkers and Personalized Medicine Shamini Selvarajah
TBC Special seminar: Next Generation Sequencing: new applications in the cancer field (1 hour) Sachin Kumar
TBC Online Final Exam (45%)

Harry Elsholtz

Sachin Kumar