Faculty Research Database

Click on "Select Profile" below to focus on up to six faculty profiles.

This is a database for faculty who have submitted a research profile. To view all LMP faculty and their contact information, go to the Faculty Contact Directory.

K

PhD, FACMG
Assistant Professor
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cancer

Research interests include application of new technologies to molecular diagnostics and the treatment of inherited disease and cancer, especially in the areas of artificial intelligence and health informatics.

Phone: 416-340-4800
Ext: 5265
MD, FRCSC, FRCOG, MRCP(UK)
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Genetics, Genomics & Proteomics

My research is focussed on basic, translational and clinical aspects of the placental complications of pregnancy, with a focus on severe pre-eclampsia and intra-uterine growth restriction (IUGR).

Phone: 416-586-8764
MBChB, PhD, FRCPath(SA), FRCPC
Associate Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Infectious Diseases & Immunopathology

Primary research interests include colorectal cancer (special focus on prognostic and predictive factors), inflammatory bowel disease and acute and chronic liver disease.           

Phone: 416-586-4800
Ext: 6187
MD, MSc, PhD
Assistant Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cancer

Cancer cytopathology, Fine needle aspiration 

Phone: 416-340-5197
MD, PhD
Associate Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Molecular & Cell Biology

The major focus of my research is the development and application of genomic technologies to the understanding of the causes of reproductive failure. Identification and characterization of copy number variation in infertile males, preimplantation embryos and perinatal samples provide insight into the mechanisms that cause infertility and abnormal embryonic development.

Phone: 416-586-4800
Ext: 3969
MD, PhD
Professor
Research Location: Toronto Western Hospital/Research Institute (UHN)
Primary Research Area: Brain & Neuroscience
Secondary Research Area: Molecular & Cell Biology

Using specialized microscopy and morphometric methods together with biochemical and genetic evaluations of human brain tissue samples our aim is to evaluate selective cellular and protein vulnerability patterns in human neurodegenerative conditions with movement disorders and cognitive decline and brain aging.

Phone: 416-340-5203
MD, PhD, FRCP, FCAP
Professor Emeritus / Emerita
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Brain & Neuroscience

Study of pituitary tumours using histology, immunohistochemistry, electron microscopy and, in collaboration, applying molecular/genetic methods. Tumour morphology is correlated with clinical findings, endocrinologic and imaging parameters. Investigations include: biomarkers, angiogenesis, biologic behaviour, prediction of prognosis and assessment of therapeutic responsiveness.

Phone: 416-864-5858
Ext: 2365
MDCM
Assistant Professor
Research Location: St. Joseph's Health Centre
Primary Research Area: Molecular & Cell Biology
Phone: 416-530-6268
MD, MSc, FRCPC
Assistant Professor
Research Location: St. Michael's Hospital/Research Institute
Phone: 416-360-4000
Ext: 6130
PhD, FCACB
Associate Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cancer, Secondary Research Area: Genetics, Genomics & Proteomics

My laboratory is focusing on using high-throughput “omics” technologies to understand disease pathogenesis, with a particular emphasis on cancer and rheumatic diseases and its application to clinical practice.   

Phone: 416-340-4800
Ext: 8589
HBSc, MSc, PhD, FCCM
Assistant Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Genetics, Genomics & Proteomics
Phone: 647-792-3171
PhD, FCACB, FABMG
Assistant Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Metabolism & Nutrition

My research focuses on genetic metabolic disorders. Currently,  the emphasis is on understanding the pathobiology of Congenital Disorders of Glycosylation as well as developing new methods for the diagnosis of this group of diseases.

Phone: 416-813-5105
Ext:

L

BSc, MSc, MD, FRCP(C)
Associate Professor
Phone: 416-864-5858
PhD
Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Hematopathology

Understanding how therapeutic antibodies can be used to treat autoimmune disease. We study the ability of novel monoclonal antibodies, as well as antibodies taken from the plasma of healthy blood donors (IVIg) to inhibit disease progression in autoimmunity. We also study how an antibody called "anti-D" is able to prevent haemolytic disease of the fetus and newborn.

Phone: 416-864-5599
PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

Our laboratory is interested in understanding the molecular mechanisms at play in the tug-of-war between viruses and the host. We want to understand how certain retroviruses enter cells and are then antagonized by innate immune molecules. Immunological recognition and restriction of viral pathogens is fundamental for fighting infectious disease.

Phone: 416-978-1060
MD, PhD, FRCPC
Associate Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Cardiovascular
Secondary Research Area: Infectious Diseases & Immunopathology

My lab has an interest in how microvascular endothelial permeability is controlled. A number of projects examine how the host-pathogen interaction affects endothelial permeability. In addition, we are investigating how the movement of critical proteins and hormones across the endothelium is regulated.

Phone: 416-864-6060
Ext: 77655
PhD, FACMG
Associate Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cancer

Dr Lerner-Ellis is a molecular geneticist who serves as Head and Director of the Advanced Molecular Diagnostics Laboratory at Mount Sinai Hospital and an Associate at the Ontario Institute for Cancer Research.  In addition to his core interests in molecular diagnostics, as applied to breast and colon cancer, a major aim of his research is to integrate genome sequencing into the general practice of medicine.     

Phone: 416-586-4800
Ext: 6115
MBBS
Lecturer
Research Location: North York General Hospital
Primary Research Area: Cancer
Phone: 416-756-6252
PhD
Assistant Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Metabolism & Nutrition
MD, FRCPC
Professor Emeritus / Emerita
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Molecular & Cell Biology

We have identified the molecules tissue factor and fgl2/fibroleukin, which are membrane associated serine proteases. These molecules play pivotal roles in the pathogenesis of viral hepatitis (fgl2/fibroleukin), allo- and xenograft rejection (tissue factor and fgl2).

Phone: 416-340-5166

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