Dr. Serge Jothy received his medical degree from the University of Bordeaux, France. He then moved to McGill University in Montreal, where he received a PhD in experimental medicine. Subsequently, he trained in anatomic pathology at Queen's University before returning to McGill and the Royal Victoria Hospital, Montreal, in a staff position. In 1997, having reached the position of Full Professor in the Department of Pathology at McGill, Dr. Jothy was at Sunnybrook Health Sciences Centre as Head, Division of Anatomic Pathology until 2001.  He joined the Department of Laboratory Medicine at St. Michael’s Hospital in 2002 where he was the Chief of the department until June 2014. 

Teaching
Dr. Jothy is actively involved in teaching and supervision of undergraduate and postgraduate trainees. 

Research
In addition to his leadership and clinical activities, Dr. Jothy is an active scientist in the area of cancer cell biology and has published over 120 peer-reviewed papers. His laboratory is investigating the mechanisms used by cancer cells to invade adjacent normal tissues and produce distant metastases. The investigations focus on how tumour cells become motile by modulating cell adhesion mechanisms.  By extension, the studies are also directed at understanding how molecular alterations in critical components of the extracellular matrix contribute to the invasion of tumour cells, and how various compounds can block tumour invasion.

The methodological approaches being utilized are based on cellular and molecular techniques. The objects of the studies are both tumour cells in culture, and cells derived from human or animal tumours. These studies are conducted in a recently built laboratory at St. Michael's Hospital, a teaching hospital of the University of Toronto.

Other Academic Activities
Dr. Jothy is active in leadership roles at the University of Toronto and in committees and organizations in the pathology community.