Chami, Rose | Laboratory Medicine and Pathobiology --- University of Toronto

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Carry out collaborative studies with clinical colleagues on clinico-pathological correlations, provisions of diagnosis and treatments and outcome of paediatric diseases. My areas of interest include paediatric tumours, pediatric renal and lung diseases.
Carry-out collaborative research with clinical colleagues using animal models to assess new modalities of treatment.

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Professor

I obtained my medical degree from the Lebanese University (Beirut, Lebanon) in 2005. I finished my anatomical pathology training with the Faculty of Medical sciences, Lebanese University (Beirut, Lebanon) and Faculty of Medicine René Descartes/Institut Curie (Paris, France) in 2010. I then went on to complete an 18 month paediatric pathology fellowship at The Hospital for Sick Children (SickKids) in 2010. I became a staff pathologist in 2012 at CHU Sainte-Justine (Montreal, Canada) and an assistant professor at the University of Montreal in 2012. I became a staff pathologist at the Hospital for Sick Children in 2014. Iam an assistant professor in the Department of Laboratory Medicine and Pathology at the University of Toronto.

Lab

Interpretation and diagnosis of surgical cases covering almost the whole spectrum of Pediatric diseases (non-neoplastic and neoplastic entities).
Interpretation and diagnosis on open lung biopsies and surgical lung resections.
Interpretation and diagnosis of skin punch biopsies and surgical skin resections.
Interpretation and diagnosis of endoscopic biopsies of the gastrointestinal tract (esophagus, stomach, duodenum, colon, rectum).
Interpretation and diagnosis of GI disease in surgically resected samples of intestine (congenital and acquired GI disease, inflammatory bowel disease, etc.) and liver.
Interpretation and diagnosis of liver biopsies for primary liver disease due to genetic-metabolic disease, congenital anomalies, infectious, surgical and neoplastic disease.
Interpretation, diagnosis and information related to treatment decisions for patients with liver, lung and intestine transplants.
Interpretation of cytology specimen (Bronchoalveolar lavage, thyroid cytopathology, serous cavity fluids …).
On-call coverage for all Pathology services (night, weekend and holidays, 365 days service) including intra-operative consultation for surgical pathology.
A. Placenta Pathology: Interpretation and diagnosis of placenta pathology.
B. Development of Special Expertise: Development of expertise in specific organ systems especially pediatric kidney disease.
C. Education:
- Teaching/Training of residents in Pathology and fellows in Pediatric Pathology.
- Teaching/Training of clinical residents and fellows in Pediatric Gastroenterology, liver disease, and chest diseases.
- Presentations at many Clinicopathologic Rounds.
- Continuing education: attend and participate at various hospital-wide rounds, and other local, national and international meetings on Pediatric and General Pathology.

Publications

1. Alhammad A, Kamath BM, Chami ROSE, Ng VL, Chavhan GB. Solitary Hepatic Nodule Adjacent to the Right Portal Vein: A Common Finding of Alagille Syndrome? J Pediatr Gastroenterol Nutr. 2016 Feb;62(2):226-32.

2. Dionne A, Kokta V, Chami ROSE, Morissette G, N Dahdah N. A case of Fatal Kawasaki – Correlation between optical coherence tomography and pathology. Pediatr Int. 2015 Dec;57(6):1174-8.

3. Chami ROSE, Marrano P, Teerapakpinyo C, Shuangshoti S, Thorner P. BRAF mutations in pediatric metanephric tumours. Hum Pathol. 2015 Aug;46(8):1153-61.

4. De Kock L, Park BK, Chami Rose, Deal CL, Priest JR, Foulkes WD. Exploring the association Between DICER1 mutations and differentiated thyroid carcinoma. J Clin Endocrinol Metab. 2014 Jun;99(6):E1072-7.

5. Bandsma RH, Sokollik C, Chami Rose, Cutz E, Brubaker PL, Hamilton JK, Perlman K, Zlotkin S, Sigalet DL, Sherman PM, Martin MG, Avitzur Y. From Diarrhea to Obesity in Prohormone Convertase 1/3 Deficiency: Age-dependent Clinical, Pathologic, and Enteroendocrine Characteristics. J Clin Gastroenterol. 2013 Nov;47(10):834-43.

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